Confirmatory evidence from 18S rRNA gene analysis for in vivo development of propamidine resistance in a temporal series of Acanthamoeba ocular isolates from a patient.

نویسندگان

  • D R Ledee
  • D V Seal
  • T J Byers
چکیده

DNA sequences of three 18S rRNA gene alleles present in trophozoites obtained before and after therapy for Acanthamoeba keratitis substantiate a previous report that the infection was due to a single Acanthamoeba strain. Thus, the possibility that propamidine resistance which developed during therapy was due to a mixed infection was ruled out.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 42 8  شماره 

صفحات  -

تاریخ انتشار 1998